Emerging Approaches in Intravenous Moderate and Deep Sedation
نویسندگان
چکیده
منابع مشابه
Pharmacokinetic considerations for moderate and deep sedation.
Moderate and deep sedation can be provided using several routes of drug administration including oral (PO), inhalation, and parental injection. The safety and efficacy of these various techniques is largely dependent on pharmacokinetic principles. This continuing education article will highlight essential principles of absorption, distribution, and elimination of commonly used sedative agents.
متن کاملPharmacodynamic considerations for moderate and deep sedation.
Moderate and deep sedation can be provided using various classes of drugs, each having unique mechanisms of action. While drugs within a given classification share similar mechanisms and effects, certain classes demonstrate superior efficacy but added concern regarding safety. This continuing education article will highlight essential principles of pharmacodynamics and apply these to drugs comm...
متن کاملModerate and deep nurse-administered propofol sedation is safe.
INTRODUCTION Non-anaesthesiologist-administered propofol sedation (NAPS/NAAP) is increasingly used in many countries. Most regimens aim for light or moderate sedation. Little evidence on safety of deep NAPS sedation is available. The aim of this study was to explore the safety of intermittent deep sedation with NAPS in patients undergoing gastroenterologic endoscopic procedures. METHODS This ...
متن کاملSympathetic and hemodynamic effects of moderate and deep sedation with propofol in humans.
BACKGROUND The objective of this study was to determine the mechanisms involved in the hypotension associated with sedative doses of propofol in humans. METHODS Ten healthy volunteers (aged 21-37 yr) participated on two occasions and in random order received placebo or propofol infusions. Standard monitoring and radial artery blood pressure were combined with measurement of forearm blood flow...
متن کاملClinical analysis of moderate-to-deep-sedation by nonmedical sedation practitioners in 597 patients undergoing gastrointestinal endoscopy: a retrospective study
BACKGROUND AND STUDY AIM The purpose of this study was to evaluate whether moderate-to-deep sedation with propofol and alfentanil can be administered safely by nonmedical sedation practitioners, and the outcomes of this practice in the Netherlands. We retrospectively analyzed the occurrence of sedation-related complications in patients undergoing gastrointestinal endoscopic procedures. PATIEN...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2021
ISSN: 2077-0383
DOI: 10.3390/jcm10081735